Notes client can't remote to domino

Last days, the Notes client can connect to the domino server normally. I encountered the error today morning.

I have setuped two domino server, one on local compute which Notes client installed on it too and another on a remote manchine. Usually, I using the Notes client to access both domino server by switching. I change the notes.ini file so that  I need to re-configure the connection information when I start Notes client. What noteworthiness is keeping the user.id file under the <Notes_data_directory> for two diferent server connection. Once you lost the user.id file maybe you need to re-setup the Notes client. Then how to modify the notes.ini file?Keep the following statements and delete all of other messages in the file:

[Notes]
KitType=1
Directory=<Notes_data_directory>

I don't think it's a good way to connect to the different domino server through one notes client. But I'm more acquaintant with this way.Today I want to connect to the remote domino server. I changed the notes.ini file and start notes client. I encountered the remote error when I re-configure the connection parameters. The prompt message says the domino server maybe down or the network communication may have trouble. I am confused for both possible problems work fine. Then I code some scripts using Java to connect to the server. I can get the ior content successfully but it threw exception--no route to host--when create session. I guess the problem may be firewall or other security settings. So I open the diiop port in the remote machine,but it failed too. I tried again and disable the firewall of the remote machine. Running the java code again, it successfully to create session. So far, something continue to confuse me. I don't know why but i can work normally now.